
Written and maintained by the PhDino author · Last reviewed 21 September 2026 · Checked against 1 independent reference calculation · how PhDino checks its numbers
Scaling a medication dose to a patient's body weight using a per-kilogram dosing rate.
Many medications, especially in pediatrics and critical care, are dosed by body weight rather than as a single fixed adult dose, since how a drug distributes through and gets cleared from the body scales substantially with body size. A dosing guideline expressed as milligrams per kilogram lets the same guideline apply sensibly across a wide range of patient sizes.
The per-kilogram dosing rate itself is a value that comes from clinical pharmacology research and published dosing guidelines specific to each drug and indication — it isn't something derived or estimated here, only applied once known.
Total dose = patient weight (kg) × dose per kilogram (mg/kg)
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The Body: A Guide for Occupants by Bill Bryson — A readable tour of human physiology — the systems behind the clinical numbers. (Bookshop.org UK, UK delivery only)
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